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模拟失重状态下大鼠前庭形态学和耳石钙含量的变化
http://www.100md.com 《第四军医大学学报》 2005年第17期
模拟失重,,模拟失重;,耳石;,空晕病;,X射线微区分析,0引言,1材料和方法,2结果,3讨论,【参考文献】
     Observation of morphology and calcium content of vestibular otoconia in rats in simulated weightlessness

    ZHANG JiangPing, PENG ZhenHui, YANG MiaoLi, WEI JunRong, XU Min

    Department of Otolaryngology, Second Hospital, Xian Jiaotong University, Xian 710004, China

    【Abstract】 AIM: To observe the morphological changes of vestibular organs and to detect the calcium content of otoconia in rats after simulated weightlessness. METHODS: The changes of vestibular organs were investigated with scanning electron microscopy and in a model of simulated weightlessness by tailsuspension, and an Xray microanalysis was conducted. RESULTS: The vestibular otoconia became small, round and irregular in shape or with fissures and were loosely arranged in rats after 160day suspension in simulated weightlessness. The calcium content of otoconia markedly decreased(P<0.01). CONCLUSION: Decreasing bone formation may be the main reason for the reducing calcium content in the otoconia. The headward distribution of blood volume may account for the morphological changes in the middle ear and inner ear. ......

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