Changes of angiotensinª²aldosterone system in CO2 pneumoperitoneum

    LI Yanª²Qin£¬ZHANG Chunª²Xian£¬FENG Shuª²Xian£¬BIAN Liª²Hua£¬LIU Qing,LI Juan

    1Department of Obstetrics & Gynecology, Anning Branch Hospital, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou 730070, China, 2Department of Obstetrics & Gynecology, Outpatient Department, Lanzhou Military Command, Lanzhou 730020, China

    ¡¾Abstract¡¿ AIM: To observe the changes of angiotensin ¢ñ (AT ¢ñ), angiotensin ¢ò (AT ¢ò) and aldosterone (ALD) levels under general anesthesia for female patients when they were under the low CO2 pneumascos and with the body posture of 30¡ã low head and high feet. METHODS: The AT ¢ñ,¢ò and ALD levels of all patients under laparoscopy were observed by RIA respectively at 10 min before insufflation, 10 min, 30 min and 60 min after insufflation and 10 min after desufflation. RRSULTS: Compared with preinsufflation, there was no significant changes in the plasma levels of AT ¢ñ, AT ¢ò and ALD after insufflation (P>0.05), but 10 min after insufflation, they were higher than those before insufflation (P<0.05). AT¢ñ and ALD were still higher 30 min after insufflation than those before insufflation (P<0.05). AT ¢ò rose obviously (P<0.01) and 60 min after insufflation, AT ¢ò and ALD were not different from those before insufflation, except for AT ¢ñ (P<0.05). After desufflation, they all returned to normal level (P<0.05). CONCLUSION: General anesthesia and low pressure (IAP 1.33-1.59) abdominnoscopy have some effects on the stress system and metabolism. ......