Graves’_____](论著)

Ｇraves’眼病131I治疗后突眼的转归与TRAb及TGA、TMA的关系

http://www.100md.com 《局解手术学杂志》 2006年第1期

Graves’,,],Graves’病；突眼；TRAb；TGA；TMA,Graves’眼病131I治疗后突眼的转归与TRAb及TGA、TMA的关系,1资料与方法,2结果,3讨论,[参考文献]

     [摘要]目的探讨131I治疗Graves’病后突眼的转归与TRAb及TGA、TMA的关系，为临床治疗Graves’病后突眼提供理论参考。方法选择伴有突眼的Graves’病患者78例进行131I治疗，在治疗后第3、6、12个月进行随访，检测其TRAb及TGA、TMA浓度。结果治疗前TRAb及TGA、TMA水平高者，治疗后眼病获得改善的可能性较大;而治疗前TRAb及TGA、TMA水平低者，治疗后其活性变化不大，眼病的改善也不明显，差异有显著性。结论TRAb及TGA、TMA水平与突眼的发生和转归关系密切。

    [关键词] Graves’病；突眼；TRAb；TGA；TMA

    Association of turnover of goggledeye due to Graves’ disease treated by 131I with the blood levels of TRAb, TGA and TMA

    HUANG Maozheng, SUN Huanfu

    (Departement of Nuclear Medicine, Baise people’s Hospital, Baise 533000, China)

    Abstract: Objective To discuss the prognosis of goggledgeye caused by Graves' disease after treated with 131I and its association with the levels of TRAb, TGA and TMA in blood. Methods A total of 78 cases of Graves' disease characterized by goggledgeye were treated with 131I, and visited at 3rd, 6th and 12th month after treatment. The blood levels of TRAb, TGA and TMA were tested before treatment and during followgup. Results The patients with high blood levels of TRAb, TGA and TMA before 131I treatment had a higher opportunity to get their eye symptoms improved, vice versa. There was a significant difference between the two kinds of patients. Conclusion The occurrence of goggledgeye and its turnover is closely related to the levels of TRAb, TGA and TMA. ......

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