Procalcitonin applied in early diagnosis of neonatal infection

    ZHU Ling-ling，SHU Gui-hua，YAN Yu，XU Xiang

    (Department of Neonate，Jiangsu Subai Hospital，Yangzhou225001，China)

    Abstract:Objective To explore the early diagnosis method of neonatal infectious diseases and to investigate the clinical significance of procalcitonin(PCT)applied to neonatal infection.Methods Serum PCT，C-reaction protein(CRP)，blood routine and blood culture were measured in a total of76infectious neonates before antibiotics were administered.Their sensi-tivities and specificities for diagnosing bacterial infection were compared.Result (1)Serum PCT sensitivity and specificity for bacterial infection were81.36%(48.59)and64.7%(11.17)respectively.(2)CRP sensitivity and specificity for bacterial in-fection were47.46%(28.59)and70.59%(12.17)，with a significant difference(P<0.01)of sensitivity and no significant difference(P>0.05)in specificity compared to serum PCT.(3)Sensitivity and specificity for bacterial infection of WBC count and(or)abnormal classification were52.54%(31.59)and52.94%(9.17)，with a significant difference(P<0.05)compared with serum PCT.Conclusion As an early neonatal infection marker ......