老年肺癌患者外周血单个核细胞hTERT基因表达
肺肿瘤,,老年人;肺肿瘤;人端粒酶反转录酶;基因表达,0引言,1对象和方法,2结果,3讨论,【参考文献】
Expression of human telomerase reverse transcriptase gene in peripheral blood mononuclear cells of lung cancer in elderly patientsHE Ping, WANG HongFeng
Cadre Ward, Second Affiliate Hospital, China Medical University, Shenyang 110004, China
【Abstract】 AIM: To investigate the significance of the expression levels of human telomerase reverse transcriptase (hTERT) gene in peripheral blood mononuclear cells of lung cancer in elderly patients. METHODS: The expression levels of hTERT were detected in 20 elderly patients with lung cancer and 10 normal elderly subjects by quantitative measurement with RTPCR. RESULTS: The expression levels of hTERT mRNA in the lung cancer patients (0.927±0.115) were significantly higher than those in normal subjects (0.408±0.124, P<0.001), without significant correlation with pathological types and clinical stages. CONCLUSION: The quantitative measurement with RTPCR for the expression levels of hTERT mRNA is an effective method in the diagnosis of lung cancer in patients who are not fit for other examinations. ......
您现在查看是摘要页,全文长 6308 字符。