疏血通治疗缺血性脑血管病的临床研究
脑缺血,,脑缺血；生物医学研究；治疗,1资料与方法,2结果,3讨论,【参考文献】
【摘要】 目的 研究疏血通注射液治疗缺血性脑血管疾病的疗效及其对血液流变学的影响。方法 选择缺血性脑血管疾病患者120例，随机分为治疗组62例及对照组58例。治疗组用疏血通8ml加入生理盐水250ml中静脉滴注，每日1次，对照组用复方丹参20ml加入生理盐水250ml中静脉滴注，每日1次，两组均连续治疗15天为1个疗程。分别在治疗前后进行神经功能缺损评分及血液流变学指标监测。结果 治疗1个疗程后，疏血通治疗组总有效率为93.6%，对照组总有效率为74.1%，两组疗效差异有非常显著性(P<0.01)，治疗组全血高切黏度、全血低切黏度、血浆黏度、纤维蛋白原指数均明显下降(P<0.01)，无不良反应。结论 疏血通注射液促进神经功能恢复的机制可能与其降低血液黏度、改善血液流变学有关，是治疗缺血性脑血管疾病的理想药物之一。【关键词】 脑缺血；生物医学研究；治疗
The clinic research on curing cerebral ischemia by Shuxuetong
ZHANG Houyun,ZHU Jie.Department of Neurology,Qianjiang National Hospital,Chongqing 409000,China
【Abstract】 Objective To observe the clinical effect of curing cerebral ischemia and dynamic detect the morheology which we can explore its effect on blood stream alteration marker by Shuxuetong.Methods We selected 120 consecutive patients with cerebrovascular ischemia and divided into two groups:indrop Shuxuetong 8ml and CoDanshen 20ml.Each group was given physiological saline 250ml.Results After treatment,in experimental treatment group,the total rate of efficiency is 93.6%,while in the Co Danshen group,the total rate of efficiency is 74.1%.The alteration is very significant(P<0.01).In experimental treatment group,it showed a dramatic descend in whole blood high viscosity,whole blood low viscosity,blood plasma viscosity,the exponent of fibrinogen(P<0.01).There are no adverse drug reaction.Conclusion The mechanism of accelerating the function of nerve by Shuxuetong might be to decline the viscosity of blood,improve the blood flow of the infarct penumbra area.It will be the most ideal medicament of curing cerebral ischemia. ......
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