Effects of lowintensity pulsed electromagnetic fields on cardiovascular system of rabbit

    LUO ErPing1,2，JIAO LiCheng1，SHEN GuangHao2，WU XiaoMing2，LU LiHua3，XU QiaoLing4,LIU LuWei5

    1Research Center of Intelligent Information Processing,School of Electronic Engineering,Xidian University,Xian 710071,China,2Department of Military Medical Equipment & Metrology,School of Biomedical Engineering,3Department of Chemistry,School of Pharmacy,4School of Nursing,5Department of Outpatient,Fourth Military Medical University,Xian 710033,China

    【Abstract】 AIM: To study the effects of exposing rabbits to lowintensity pulsed electromagnetic fields (PEMFs) on the cardiovascular system.METHODS: Thirty female white bigeared rabbits were randomly divided into three groups.Normal group was fed with normal diet,the other two groups were fed with hypercholesterolemic diet but the magnetic group was fed in 15 Hz pulsed electromagnetic fields (8×10-4 T and 10 h/d).After eight weeks,the levels of blood lipid,indexes of hemorheology,and properties of cardiac function were examined.Gross anatomy of thoracic aorta was performed.The histomorphologic changes of hepatic and myocardial tissues were compared.RESULTS: ① Compared with those in hyperlipid group,the hemorheology indexes in magnetic group reduced significantly (P<001).Compared with those in normal group,the indexes of whole blood viscosity of high shear rates (ηb1),whole blood reduction viscosity of high shear rates (ηb2′) and aggregation indexes of RBC (AI) increased in magnetic group (P<001).② Compared with those in hyperlipid group,the levels of serum total cholesterol and triglyceride decreased evidently in magnetic group (P<001),while the high density lipoprotein (HDL) value increased obviously (P<001).No difference was found in the values of triglyceride and HDL between the magnetic group and control group (P>005).③ Compared with those in hyperlipid group,the properties of cardiac function in magnetic group showed statistically significant differences (P<001) while no difference was found in LVET,PEP,ICT and ICT/LVET between magnetic group and control group (P>005).④ The deposit of fatty material on the inner lining of thoracic aorta wall in magnetic group was significantly lighter than that in hyperlipid group.⑤ The accumulation of fat in hepatic tissue in hyperlipid group was much more notable than that in magnetic group.No notable steatosis was observed in magnetic and control group.⑥ Numerous aggregation of lipoids emerged among the myocardial myofibrils in heperlipid group while no notable changes were found in both magnetic and control group.CONCLUSION: Lowintensity PEMFs are helpful to the prevention and treatment of cardiovascular diseases. ...... 濡傛灉鎮ㄥ湪浣跨敤鎵嬫満绛夋祦瑙堟椂鏃犳硶鏌ョ湅鎴栦笅杞藉叏鏂囷紝鍙兘鏄鎼滅储寮曟搸澶辩湡鈥滆浆鐮佲€濓紝璇风偣鍑诲睆骞曟渶涓嬫柟鐨勨€滅數鑴戠増鈥濇垨鈥滃師缃戦〉鈥濊闂€�


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