Comparison of helical CT scanning with different dynamic enhancements in diagnosis of small hepatic carcinoma

    GUO Xiaoª²Juan,GUO Youª²Min,CHEN Min,ZHANG Shaoª²Juan,YANG Jian,JIN Chenª²Wang

    Imaging Center,First Hospital,Xi¬ðan Jiaotong University,Xi¬ðan 710061£¬China

    ¡¾Abstract¡¿ AIM: To compare the performance of two dynamic enhancements for helical CT scanning in the diagnosis of small hepatic carcinoma by Meta analysis (the late arterial phase A2+portal venous phase P+delayed phase D,the early arterial phase A1+late arterial phase A2+portal venous phase P) and to assess their clinical value.METHODS: Pubmed,Ovid,Embase databases (1990/2004) and CNKI database (1994/2004) were searched for the related articles in English and Chinese respectively.By the assessment standard of Evidenceª²based Medicine,English and Chinese literature on the dynamic enhancement for helical CT scanning was screened.Pooled weighted sensitivity,pooled weighted specificity,pooled weighted lnDOR and the area under SROC were used to assess the performance of two types of threeª²phased dynamic enhanced scanning of helical CT in the diagnosis of small hepatic carcinoma.RESULTS: Altogether 11 articles in English that met the standard were included,6 of which used A2+P+D dynamic scanning and 5 of which used A1+A2+ P dynamic scanning.The pooled weighted sensitivity of the two types was 84% and 88% respectively,the pooled weighted specificity of them was 94% and 85% respectively and the pooled weighted lnDOR was 4ª±50 and 3ª±91 respectively.The area under SROC curve was 89ª±12% and 90ª±28% respectively (P>0ª±05).CONCLUSION: Considering the overall sensitivity and specificity, the two types of helical CT dynamic enhancements both have high accuracy in the diagnosis of small hepatic carcinoma,but the approach of A1+A2+P was higher in its sensitivity and A2+P+D was higher in the specificity.The latter has a higher clinical value for its easy operation and relatively low requirement of equipment. ......