【摘 要】 目的 比较曲马多和哌替啶对剖宫产患者术中抗寒战的效果及副作用，为其临床合理应用提供参考。 方法 将90例硬膜外麻醉后发生寒战产妇随机分为对照组、哌替啶组和曲马多三组，分别在发生寒战后注射生理盐水、哌替啶0.5mg/kg和曲马多1mg/kg，比较注射后产妇寒战的改善程度、患者的不良反应、新生儿Apgar评分。 结果 应用曲马多和哌替啶后患者对寒战的明显改善率为96.6%和80.0%，两组间无明显差异，而生理盐水组明显改善率为10.0%，与曲马多和哌替啶组相比差异有显著性。哌替啶组的不良反应总体发生率明显高于曲马多组和对照组。新生儿Apgar评分哌替啶组为8.3±1.2，明显低于曲马多组的9.6±0.5和生理盐水组的9.5±0.5。 结论 曲马多比哌替啶更适用于治疗剖宫产患者术中寒战反应。

    【关键词】 剖宫产术;曲马多;麻醉，硬膜外;寒战

    Clinical study of tramadol for the treatment of postepidural anesthetic shivering in parturients TONG Lei，WANG Hong-wei，CHEN Wu-rong，et al.(Department of Anesthesiology，Putuo Affiliated Hospital of Shanghai Univrsity of Chinese Traditional Medicine，Shanghai200062，China)

    【Abstract】 Objective To compare the efficacy and side effects of tramadol and pethidine for the treatment of postepidural anesthetic shivering in parturients.Methods Ninety parturients who shivered during cesarean delivery under epidural anesthesia and requested antishivering treatment were randomly divided into three groups:Group T(n=30)received tramadol1.0mg/kg ......