延边地区朝、汉族慢性乙型肝炎患者血清标志物与HBV DNA定量的关系
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沈哲式, 金仁顺, 朴东明, 张英哲
朝族;汉族;荧光定量PCR;乙型肝炎病毒DNA;乙型肝炎病毒;血清标志物,延边地区朝、汉族慢性乙型肝炎患者血清标志物与HBVDNA定量的关系,沈哲式,金仁顺,朴东明,张英哲,通讯作者,Relation
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沈哲式, 金仁顺, 朴东明, 张英哲, 延边大学医院病理科 吉林省延吉市 133000
通讯作者: 朴东明, 133000, 吉林省延吉市局子街119号, 延边大学医院病理科. pdm1117@hotmail.com
电话: 0433-2660121 传真: 0433-2513610
收稿日期: 2006-02-27 接受日期: 2006-03-29
Relationship between hepatitis B virus serum markers and hepatitis B virus DNA quantities in Korean and Han patients with chronic hepatitis B in Yanbian area
Zhe-Shi Shen, Ren-Shun Jin, Dong-Ming Piao, Ying-Zhe Zhang
Zhe-Shi Shen, Ren-Shun Jin, Dong-Ming Piao, Ying-Zhe Zhang, Department of Pathology, Hospital of Yanbian University, Yanji 133000, Jilin Province, China
Correspondence to: Dong-Ming Piao, Department of pathology, Hospital of Yanbian University, 119 Juzi Street, Yanji 133000, Jilin Province, China. pdm1117@hotmail.com
Received: 2006-02-27 Accepted: 2006-03-29
Abstract
AIM: To investigate the relationship between the HBV markers (HBV M) and contents of HBV DNA in Korean and Han patients with chronic hepatitis B (CHB) in Yanbian area.
METHODS: The contents of HBV DNA and the levels of HBV M were detected in 1773 patients (Korean, n = 1074; Han, n = 699) with CHB by fluorescence quantitative polymerase chain reaction (FQ-PCR) and enzyme linked immunosorbent assay (ELISA), respectively. The data were comparatively analyzed between the two ethnic groups.
RESULTS: For HBV M, Korean and Han patients covered percentages of 40.69% and 47.07% (P < 0.01), respectively, in group A (HBsAg+, HBeAg+, HBcAb+), 47.07% and 38.34% (P < 0.05), respectively, in group B (HBsAg+, HBeAb+, HBcAb+), and 7 ......
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