胰蛋白酶原2在AP诊断中的作用及与淀粉酶和脂肪酶的对比实验
白酶,,],尿胰蛋白酶原2;急性胰腺炎;淀粉酶;脂肪酶,1材料、对象和方法,2结果,3讨论,参考文献:
[摘 要] 目的:探讨尿胰蛋白酶原2在急诊急性胰腺炎(AP)诊断中的应用及与淀粉酶、脂肪酶的比较。方法:尿胰蛋白酶原2采用免疫层析法,淀粉酶采用PNPG7法,脂肪酶采用比浊法。对急诊AP病人59例在入院时进行上述三个项目的测定。对照组为诊断为非胰腺炎的病人。结果:AP患者中有58例胰蛋白酶原2为阳性,诊断敏感性、特异性、阳性预期值和阴性预期值分别达到98.3%、92%、93.5%和97.9%,明显高于淀粉酶和脂肪酶,AP组和对照组差别有统计学意义。结论:胰蛋白酶原2具有简便、快速、准确的优点,是急诊诊断AP的一个良好的指标。[关键词] 尿胰蛋白酶原2;急性胰腺炎;淀粉酶;脂肪酶
The Role of Urinary Trypsinogen2 in Diagnosis of Acute Pancreatitis and Comparing with Amylase and Lipase
LIU Hui
(Wucheng Planned Parenthood Service station, Wucheng, Shandong 253300, China)
Abstract:Objective To inverstigate the role of urinary trypsinogen2 in diagnosis of acute pancreatitis and comparing with amylase and lipase.Methods To measure urinary trypsinogen2 with immunochromatography,AMY with method by PNPG7,LIP with immunoprecipitation.48 patients with AP were measured three items when admitted to hospital.The control group contains patients without AP.Results Urinary trypsinogen2 of 58 patients with AP were positive.The sensitivity,specificity,positive predicting rate and negative predicting rate were 98.3%,92%,93.5%,97.9%.They are much higher than that of AMY and LIP.The difference between the AP group and control group has statistics significance.Conclusion Urinary trypsinogen2 has simple, quick and accurate advantage.It is a better maker for diagnosis of AP. ......
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