Treatment of acute bacterial infection with gatifloxacin mesylate glucose injection: 48 cases report

    WU Yin1, WEN Aiª²Dong1, WU Changª²Gui2, WANG Hanª²Ming3, JIAN Wen2, XU Guoª²Shuang3, ZHAO Lei1, SHI Ru1

    1Department of Pharmacy, 2Department of Respiratory Medicine, 3Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi¬ðan 710033, China

    ¡¾Abstract¡¿ AIM: To observe the curative effect and safety of gatifloxacin mesylate glucose injection for acute bacterial infection. METHODS: Fortyª²eight cases of acute bacteria respiratory or urinary tract infection were iv divided into two groups doubleª²blindedly and randomly. The experimental subjects of the two groups were given an injection of gatifloxacin mesylate glucose or hydrochloric acid levofloxacin 200 mg (bid) for 7 to 14 days respectively. The curative effect and the adverse reaction were evaluated. RESULTS: In experimental group, the rate of clinical curative effect, the bacterial clearance rate, the bacterial sensitivity rate and the incidence of adverse reaction were 90.9%, 94.7%, 100.0% and 13.6% respectively, and 88.5%, 95.4%, 100.0%, and 19.2% respectively in control group. There was no significant differences in the curative effect and safety between 2 groups (P>0.05). CONCLUSION: Gatifloxacin mesylate glucose injection is clinically effective and safe for common sensitive bacterial infection. ......