【摘要】 目的 明确邵阳市区成年居民脂肪肝患病率及其主要的危险因素。方法 通过多阶段分层随机抽样，对邵阳市3个城区26个社区18岁以上居民进行调查，调查的内容涉及问卷调查、体格检查、生化检测及肝胆B超检查。结果 5267例成人完成调查，占邵阳市区总人口的1.24%，脂肪肝患病率为24.2%，男性明显高于女性，脂肪肝组收缩压、舒张压、BMI、空腹血糖、TG、TCH、LDL-C、超重肥胖、高血糖、血脂异常和高血压患病率均明显高于非脂肪肝组(P<0.05)，多因素分析结果显示，体重指数、甘油三酯、胆固醇、文化程度和舒张压等5项指标与脂肪肝密切相关。结论 邵阳市区成年居民脂肪肝患病率高，超重肥胖及其相关的多元代谢紊乱与脂肪肝关系密切。

    【关键词】 脂肪肝；流行病学；患病率；危险因素

    Epidemiological survey of prevalence of fatty liver and its risk factors in a general adult population of Shaoyang

    CHEN Jin-yong,ZHANG Guo-hua,LUO Zheng-ren,et al.Shaoyang Central Hospital,Shaoyang 422000,China

    【Abstract】 Objective To investigate the prevalence and major risk factors of fatty liver among adult residents in Shaoyang.Methods A cross-sectional survey with multiple-stage stratified cluster and randomized sampling was performed.All residents aged 18 and above were invited to participate in the survey.They came from 26 communities of Daxiang District,Shuanqing District and Beita District.Questionnaire,physical examination,biochemistry test and ultrasonographic examination of liver and gallbladder were undertaken.Analysis of data was performed through SPSS 13.0 for Windows statistical package.Results A total of 5267 residents took part in the survey,which was 87.8% of adult residents of the investigated communities and 1.24% of Shaoyang municipal residents.The prevalence of fatty liver was 24.2%.The prevalence of fatty liver in males was more higher than females.The mean systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),fasting serum glucose level,triglyceride(TG),total cholesterol(Tch),low-density lipoprotein cholesterol(LDL-ch),and the prevalence of ultra-body mass,obesity,high serum glucose,dyslipidemia and hypertension in the fatty liver group was significantly higher than those in the group without fatty liver (all P<0.05).Logistic regression analysis demonstrated that the prevalence of fatty liver was positively correlated to five risk factors,including BMI,TG,Tch,educational level and diastolic blood pressure.Conclusion There is a high prevalence of fatty liver among adult residents in Shaoyang.Metabolic disorders such as ultra-body mass and obesity,high serum glucose,dyslipidemia and hypertension are closely associated with fatty liver in Shaoyang. ......