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编号:11123426
HBeAg(-)乙型肝炎后肝硬化的临床特征
http://www.100md.com 焦以庆, 刘 萍
乙型肝炎病毒e抗原;乙型肝炎;肝硬化;临床特征,焦以庆,刘萍,通讯作者,Clinicalcharacteristicsofpatientswithhepat
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     焦以庆, 北京地坛医院肝炎一科 北京市 100011

    刘萍, 北京地坛医院检验科 北京市 100011

    通讯作者: 焦以庆, 100011, 北京市东城区地坛公园13号, 北京地坛医院肝炎一科. jyq1898@sina.com

    电话: 010-64211031-2303

    收稿日期: 2006-03-20 接受日期: 2006-04-06

    Clinical characteristics of patients with hepatocirrhosis after HBeAg-negative

    hepatitis B


    Yi-Qing Jiao, Ping Liu

    Yi-Qing Jiao, the First Department of Hepatitis, Beijing Ditan Hospital, Beijing 100011, China

    Ping Liu, Department of Laboratory, Beijing Ditan Hospital, Beijing 100011, China

    Correspondence to: Yi-Qing Jiao, the First Department of Hepatitis, Beijing Ditan Hospital, Beijing 100011, China. jyq1898@sina.com

    Received: 2006-03-20 Accepted: 2006-04-06

    Abstract

    AIM: To conclude the clinical characteristics of hepatocirrhosis after HBeAg-negative hepatitis B (HB).

    METHODS: Three hundred and seventy-one patients with hepatocirrhosis after HB, from January to June in 2005, in Beijing Ditan Hospital, were classified into three groups: HBVDNA(+)HBeAg(+), HBVDNA(+)HBeAg(-), and HBVDNA(-)HBeAg(-), named group A, B, and C, respectively. The incidence rates of severe hepatitis and liver cancer, liver function and the level of blood lipid were observed.

    RESULTS: The incidence rate of liver cancer was significantly higher in group B than that in group A or C (31.3% vs 19.2%, 18.2%, both P < 0.05). The incidence rate of severe hepatitis was not significantly different between all the groups. The levels of albumin (ALB), pro-albumin (PAB), and cholinesterase (ChE) were reduced remarkably in group A (P < 0 ......

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