【摘要】 目的 探讨红霉素作为胃动素激动剂对胰十二指肠切除术后胃瘫的治疗效果。方法 针对常规治疗效果不明显的胰十二指肠切除术后11例胃瘫患者，给予乳糖酸红霉素静脉滴注，每日1～2次。结果 11例患者均康复出院，胃瘫持续时间最短14天，最长37天，平均21.6天。结论 胰十二指肠切除术后胃瘫的治疗原则应采用促胃肠动力药物联合全胃肠外营养支持的保守治疗措施，红霉素作为一种胃动素激动剂治疗胃瘫有良好的疗效。

    【关键词】 红霉素；胰十二指肠切除术；胃瘫

    【Abstract】 Objective To explore the beneficial effect of erythromycin on gastric stasis after pancreatoduodenectomy.Methods Administration of erythromycin lactobionate as 1g added to 5% Glucose injection 500ml for intravenous drip, bid.Results Eleven subjects recovered after erythromycin administration, and the duration of gastric stasis varied between 14 and 37 days with the means of 21.6 days.Conclusion As a motilin agonist, erythromycin proved therapeutic effect on functional delayed gastric emptying after pancreatoduodenectomy.

    【Key words】 erythromycin; pancreatoduodenectomy; gastric stasis

    胃瘫(gastric stasis)通常指腹部手术后出现的无胃流出道梗阻、而以胃排空障碍为主要特征的胃动力功能紊乱综合征 ......