【摘要】 目的 探讨联合检测5’-NT、ADA、GGT在肝细胞性黄疸和阻塞性黄疸鉴别诊断中的价值。方法 对本院40例健康人群、35例急性黄疸型肝炎和21例阻塞性黄疸病人的血清进行了5’-NT、ADA、GGT、ALT、ALP五种酶活性平行检测，并做对比分析。结果 5’-NT、GGT结果在急性黄疸型肝炎组、梗阻性黄疸组中均有非常显著增高，且其阳性率均为100%。而ADA在急性黄疸型肝炎组中虽只有88.5%阳性率，但其在梗阻性黄疸组中有非常低的阳性率，在两病例组中差异有非常显著性。结论 5’-NT、ADA、GGT的联合检测是诊断梗阻性黄疸的良好指标，若3项指标均增高，则为肝细胞性黄疸；若5’-NT、GGT显著增高，而ADA正常则为梗阻性黄疸。

    【关键词】 5’-核苷酸酶；腺苷脱氨酶(ADA)；γ-谷氨酰基转移酶(GGT)；黄疸

    【Abstract】 Objective Discussing measure 5’-NT, ADA, GGT jointly in liver cellular jaundice and obstructive jaundice on the differential diagnosis.Methods To 40 healthy crowds of our hospital, 35 cases acute jaundice type hepatitis and 21 cases obstructive jaundice, the patients serum go on 5 ’-NT, ADA, GGT, ALT, ALP five kinds enzyme activity parallel measured, make compare and analyse. Results 5 ’-NT, GGT result in acute icterohepatitis group and in obstructive jaundice has extremely remarkably increased, its positive rates are 100%. But ADA in acute icterohepatitis group although only then 88.5% positive rates, but it has the extremely low positive rates in obstructive jaundice group, has the extremely remarkable difference in two illness groups. Conclusion 5’-NT, ADA, GGT union examination is diagnoses obstructive jaundice the good targets, if three targets raises, then for liver cellular jaundice; If 5’-NT, GGT remarkably raises, but ADA is normal then for obstructive jaundice. ......