诊断__(期刊论文)

VogtKoyanagiHarada综合征误诊分析

http://www.100md.com 《广东药学院学报》 2006年第1期

诊断,,VogtKoyanagiHarada综合征；诊断；误诊,1对象与方法,2结果,3讨论,参考文献:

     摘要:目的分析VogtKoyanagiHarada(VKH)综合征的临床特点和误诊原因。方法对54例VKH综合征的患者(108只眼)的眼部表现、全身症状、荧光素眼底血管造影(fundus fluorescein angiography,FFA)和误诊情况进行回顾性分析。结果 54例VKH综合征中，33例(61.1%)患者有前驱症状，72只眼(66.7%)主要表现为后葡萄膜炎，20只眼(18.5%)以前葡萄膜炎为主，30例患者(55.6%)有皮肤、毛发和神经系统等眼外异常,有21例(38.9%)曾被误诊为其他疾病或笼统地诊断为葡萄膜炎。结论 VKH综合征是以后葡萄膜炎起病，逐渐出现前葡萄膜炎反复发作为特征的全葡萄膜炎，常伴有皮肤、毛发和神经系统等异常，本病致盲率高，容易误诊、漏诊，应加强对本病的认识，减少盲目的发生。

    关键词:VogtKoyanagiHarada综合征；诊断；误诊

    Analysis of the misdiagnosis of VogtKoyanagiHarada syndrome

    CHEN Xuemei,HUO Lijun,ZHANG Xuefen,LIAO Ruiduan，LIN Xianxuan

    (Department of Ophthalmology,The First Affiliated Hospital of Sun Yetsen University,Guangzhou 510080，China)

    Abstract: Objective To investigate the clinical features and states of misdiagnosis in VogtKoyanagiHarada (VKH) syndrome. Methods Eyes manifestations,general conditions,fundus fluorescein angiography (FFA) and states of misdiagnosis were analyzed retrospectively in 54 patients. Results In 54 patients of VKH syndrome,prodromes were noted in 33 cases(61.1%). Posterior uveitis was the main manifestation in 72 eyes (66.7%) and anterior uveitis in 20 eyes(18.5%). Abnormities of skin,hair and nervous system was found in 30 cases (55.6%). Other diseases and other types of uveitis were diagnosed in 21 cases (38.9%).Conclusions VKH syndrome is characterized by posterior uveitis in the early stage,followed by a generalized uveitis with a recurrent anterior uveitis and often accompanied by abnormities of skin,hair and nervous system. VKH syndrome can cause blindness,misdiagnosis and missed diagnosis easily. Only if to improve recognize to this disorder,make the correct diagnosis and a systemic treatment early,and the occurrence of blind can be cut down. ......

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