慢性乙型肝炎_____](中国医学)

慢性乙型肝炎患者血清和胃黏膜乙型肝炎病毒与肝胃不和证的关系

http://www.100md.com 《中西医结合学报》 2005年第1期

慢性乙型肝炎,,],慢性乙型肝炎；慢性胃炎；肝胃不和证；乙型肝炎病毒,1资料与方法,2结果,3讨论,[参考文献]

     [摘要] 目的：探讨慢性乙型肝炎患者胃黏膜乙型肝炎病毒(hepatitis B virus, HBV)与中医肝胃不和证的关系。方法：选择符合条件的慢性乙型肝炎肝胃不和证患者30例，并以慢性胃炎肝胃不和证患者30例为对照，采集空腹血液标本，进行电子胃镜检查，取胃窦、胃体、胃底黏膜；用核酸扩增荧光定量法检测血清、胃黏膜HBVDNA，综合分析各检测值对肝胃不和证积分的意义。结果：(1)慢性乙型肝炎肝胃不和证组的脘胁胀闷疼痛、嗳气呃逆以及肝胃不和证总积分明显低于慢性胃炎肝胃不和证组(P<0.01)。(2)慢性乙型肝炎组患者血清和胃窦、胃体、胃底黏膜HBVDNA检出率分别为56.7%、76.7%、76.7%、70.0%，血清、各处胃黏膜HBVDNA滴度呈正相关(r=0.66～0.94,P<0.01),且与肝胃不和总分呈正相关(r=0.36～0.52,P<0.05)，以胃体HBVDNA与肝胃不和总分相关性最密切(r=0.52,P< 0.01)。结论：慢性乙型肝炎患者肝胃不和证与胃黏膜HBV感染有关。

    [关键词] 慢性乙型肝炎；慢性胃炎；肝胃不和证；乙型肝炎病毒

    Relationship between hepatitis B virus in gastric mucosa and syndrome of disharmony between liver and stomach in patients with chronic hepatitis B

    XIA JinYu, ZHOU YaoYong, ZHAO YouYun

    (Department of Infectious Diseases, The fifth affiliated Hospital, SUN Yatsen University, Zhuhai, Guangdong Province 519000, China; Department of Integrated Traditional Chinese and Western Medicine, Tianjin Municipal Hospital of Infectious Diseases, Tianjin 300192, China; Division of Molecular Biology, Department of Clinical Laboratories, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430061, China) ......

百拇医药网 http://www.100md.com/html/DirDu/2006/05/31/98/10/06.htm

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