西洛他唑对冠状动脉小血管病变支架术后患者的长期疗效
西洛他唑,,西洛他唑;氯吡格雷;再狭窄,0引言,1对象和方法,2结果,3讨论,【参考文献】
Longterm effects of cilostazol on clinical outcomes after coronary stent implantation in smallvessel lesionsWANG ShouLi, HAN YaLing, JING QuanMin, WANG ZuLu, WANG DongMei, DENG Jie, YANG GuiTang, YU HaiBo
PLA Institute of Cardiovascular Research, General Hospital, Shenyang Military Command, Shenyang 110016, China
【Abstract】 AIM: To evaluate the effects of cilostazol on smallvessel lesions and longterm clinical outcomes in patients receiving coronary stent implantation. METHODS: One hundred and ninetythree patients who had underwent coronary stenting were randomly assigned to two groups after operation. Ninetyeight patients who had been taking aspirin 100 mg/d were given clopidogrel treatment 75 mg/d for 3 months in control group and 95 patients were given clopidogrel treatment 75 mg/d for 3 months plus cilostazol 200 mg/d for 6 months in treatment group. Angiographic followup was carried out at 6 months and clinical followup at 1 year after stenting. RESULTS: Angiographic restenosis occurred in 12 of the 53 patients (23%) in the treatment group and 17 of 52 patients (33%) in the control group (P>0.05). By the end of 1 year followup after operation, no difference was found in the rates of readmission due to cardiac and cerebral vascular diseases and no difference was found in the sideeffects of drugs such as hemorrhage between the two groups. CONCLUSION: Cilostazol treatment after PCI is safe and the treatment with cilostazo can decrease the rate of restenosis. ......
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