Clinical application of three microcirculation examination techniques in aged patients with peripheral arteriosclerotic occlusive disease

    LIU Liang1, LI Xiaoª²Ying1, LI Tieª²Ling1, ZHAO Xiuª²Mei2, LIU Xiuª²Hua2

    1Department of Geratology, 2Institute of Basic Medical Science, PLA General Hospital, Beijing 100853, China

    ¡¾Abstract¡¿ AIM: To investigate the practical value of three different microcirculation examination techniques (the nailfold microcirculation, laser Doppler perfusion imaging and transcutaneous oxygen pressure) in aged patients with peripheral arteriosclerotic occlusive disease (PAOD). METHODS: Fortyª²eight male aged PAOD patients, selected from the hospitalized patients in PLA General Hospital, were treated with Lipoª²PGE1. Before and after the treatment, the changes of clinical symptoms, ankle/brachia index (ABI), the nailfold microcirculation, laser Doppler perfusion imaging (LDPI) and the transcutaneous oxygen pressure (TcPO2) of dorsum pedis were observed. RESULTS: After treatment, the clinical symptoms of the patients were alleviated greatly (effective rate=85%). Significant differences of the three microcirculatory indexes were found before and after treatment. LDPI and transcutaneous oxygen pressure of dorsum pedis were improved significantly (P<0.05). The nailfold microcirculation total scores decreased significantly (P<0.05). CONCLUSION: The three techniques of microcirculation examination are of good practical value in assessing clinical effects in aged patients with PAOD. ......