【摘要】 目的 观察静脉应用胺碘酮治疗急性心肌梗死(AMI)并心房颤动(AF)的临床疗效及安全性。方法 对33例AMI并AF患者，先用胺碘酮静脉注射负荷量后，继以静脉滴注维持。观察房颤转复、血压、心室率以及不良反应。结果 AF转复率2h内为42.4%(14/33)，24h内为66.7%(22/33)，48h内为84.9%(28/33)，72h内为87.9%(29/33)。用药24h后心室率明显下降，与治疗前比较差异有显著性(P<0.001)。用药前后血压变化不明显(P>0.05)。2例用药后出现长R-R间期，2例出现窦性心动过缓，经停药或减量恢复。结论 静脉应用胺碘酮治疗AMI并AF安全、有效，值得临床推广应用。

    【关键词】 急性心肌梗死；胺碘酮；心房颤动

    Clinical observation of amiodarone in treatment of acute myocardial infarction with atrial fibrillation

    CHEN Bo-liang，CHEN Ke-jia.ICU，Pengbai Memorial Hospital of Haifeng County，Haifeng 516400，China

    【Abstract】 Objective To investigate the efficacy and safety of amiodarone in treatment of acute myocardial infarction (AMI) with atrial fibrillation(AF). Methods Thirty-three AMI cases with AF were observed. After a load dose，intravous amiodarone administered continuously. Efficacy of amiodarone in the reversion of AF ......