【摘要】 目的 通过测定血清C-反应蛋白(CRP)及末梢血中性白细胞,确定感染性质,并为临床判断疗效及合理使用抗生素提供依据。方法 患儿194例末梢血白细胞总数小于10×109/L，测血清CRP，异常者经治疗后复查,并进行统计学分析。结果 全部病例中CRP异常者65例,占32.5%;中性白细胞异常者37例,占19.2%,说明CRP能更好地反映细菌感染的存在; CRP异常者65例经过治疗后进行复查,临床症状好转,CRP恢复正常。CRP可以作为感染恢复的监控指标, 与末梢血中性白细胞数比较在统计学上差异有显著性(P<0.01)。结论 CRP较末梢血中性白细胞能更好地反映和检测细菌感染的存在,并为临床判断疗效及合理使用抗生素提供依据。

    【关键词】 C-反应蛋白； 中性白细胞； 细菌感染

    【Abstract】 Objective To ensure bacterial infection by examines C-reactive protein (CRP) and neutrophil leukocytes count (WBC) in order to find out bacterial infection and afford evidence in clinical treatment and in reasonable using antibiotic. Methods In 194 cases with WBC lower than 10×109/L, CRP were examined in； 65cases of them were high and were rechecked after treatment and compare CRP and neutrophil leukocytes count (WBC) by statistics.Results The level of CRP was increased in 65cases and retio of neutrophil in 37cases, their ratio were 32.5% and 19.2%, respectively. It is proved that CRP had much more value than the ratio of neutrophil in finding bacterial infection. After being treated, 65 cases were examined and the level of CRP was recovered. CRP can be regarded as an index in the recovery of infection. There were significantly different between CRP and retio of neutrophil in leukocytes (WBC) (P<0.01). Conclusion CRP was more value than retio of neutrophil in WBC in finding and examining bacterial infection, and a reasonable evidence in clinical treatment and in using antibiotics. ......