酒精性晚期股骨头缺血性坏死
酒精性,,酒精性;,晚期;,股骨头坏死,摘要,关键词,1临床资料,2讨论,参考文献
摘 要:[目的]探讨酒精性晚期股骨头坏死与长期、过量饮酒的关系。[方法]回顾本院165例人工全髋关节置换病例。分析其中27例酒精性晚期股骨头坏死的临床资料,结合文献复习,探讨酒精性股骨头坏死的发病机理。长期大量饮酒与股骨头缺血性坏死、血液生化学和凝血功能等之间的关系。比较文献报道的实验结果有何异同。[结果]大量长期饮酒可导致股骨头坏死,是多方面因素综合的结果;日均饮酒750 ml以上者,有发生晚期双侧或单侧股骨头坏死的危险;血液生化观察指标无明显改变,但与凝血功能降低有关;股骨头坏死与髋关节的骨性关节炎可同时发生。[结论]长期大量饮酒,日均饮酒量大于750 ml以上者,有导致股骨头坏死的可能;血液生化的改变无特异性的意义;坏死的严重程度与酒量多少、时间长短有关;酒精性股骨头缺血性坏死的晚期患者,行人工全髋关节置换应是最佳选择,但这类患者术中术后有渗血较多的倾向。关键词:酒精性; 晚期; 股骨头坏死
Advanced alcoholic osteonecrosis of femoral head∥LUO YuChen,XIAO Gang,CHEN Jin,et alZhanjiang Medical Central,Zhanjiang 524037
Abstract:[Objective]To discuss the relationship between AAONFH(advanced alcoholic osteonecrosis of femoral head)and extended overdose drinking[Method]Reviewed 165 cases of total hip arthroplasty,to analyzed the clinical data among 27 AAONFH cases,reviewed the literatures,discussed the pathogenesis of AAONFH and the relationship between blood biochemistry and blood cloting funtion and compared the experimental results among literatures[Result]Theres various factors resulted in osteonecrosis of the femoral head associated with alcohol longterm over intakeIndividuals consuming more than 750 ml of alcohol daily were at greater risk of double or half ONFH,Theres no change in biochemical test,but blood clotting funtion in this case would degrade,osteoarthritis of hip would synchronize[Conclusion]Individuals consuming more than 750 ml of alcohol daily have the potentiality of ONFH;Its no specificity significance in biochemical test,the necrosis extent of the femoral head is relative to the capacity and times of alcohol intakeTHR(total hip replacement)is the best treatment for AAONFH,but theres more staxis potentiality in this cases ......
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