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编号:11023682
不同疗法对格林-巴利综合征短期疗效的评估
http://www.100md.com 《中华现代内科学杂志》 2006年第6期
免疫球蛋白,,格林-巴利综合征;免疫球蛋白;血浆交换;激素,1资料与方法,2结果,3讨论,【参考文献】
     【摘要】 目的 评估不同治疗方法对格林-巴利综合征的短期疗效。方法 回顾性收集应用血浆交换、静脉用免疫球蛋白和激素不同治疗的45例格林-巴利综合征住院患者的临床资料。结果 接受单膜血浆交换或双膜血浆吸附治疗的24例患者和16例接受免疫球蛋白治疗中的11例患者,临床表现迅速改善。在免疫球蛋白治疗组中有5例患者和接受甲基强的松龙冲击治疗的全部5例患者,临床改善不明显。结论 血浆交换或吸附的治疗效果最好,免疫球蛋白的治疗作用次之,激素治疗效果不明显。

    【关键词】 格林-巴利综合征;免疫球蛋白;血浆交换;激素

    Evaluation of the shortterm efficacy of the different managements on patients with GullainBarre syndrome

    GUI Dechao,GENG Tongchao,KONG Lingqin.

    Department of Neurology, ChinaJapan Frienship Hospital, Beijing 100029, China

    【Abstract】 Objective To evaluate the shortterm efficacy of the different managements on patients with GullainBarre syndrome.Methods Retrospectively collected the data of 45 inpatients with GullainBarre syndrome treated with plasmapheresis of single filtration or double absorption, immunoglobulin intravenously and steroids.Results The clinic manifestations of all of 24 cases treated with the plasmapheresis of single filtration or double absorption, and 11 of 16 cases treated with immunoglobulin intravenously were improved. 5 cases in immunoglobulin treated group and 5 cases pulsed with steroid did not show obvious improvement.Conclusions Our data indicated that plasmapheresis of single and double filtration had the best outcome in shortterm, the next was immunoglobulin intravenously management, and the last was steroid. ......

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