五福心脑清对多发性脑梗死性痴呆大鼠的保护作用
五福心脑清；多发脑梗死性痴呆；SOD；MDA,,五福心脑清；多发脑梗死性痴呆；SOD；MDA,【摘要】,【关键词】,1材料与方法,2结果,3讨论,【
【摘要】 目的 观察五福心脑清对多发性脑梗死大鼠的保护作用。方法 采用同种大鼠自然干燥血凝块颈内动脉注入制备多发性脑梗死性痴呆大鼠模型，测定多发性脑梗死大鼠血清SOD、MDA的含量,观察脑组织形态学改变。结果 模型组血清SOD的含量下降，MDA的含量增高；复方丹参滴丸和五福心脑清各剂量组均可增高SOD的含量，降低MDA的含量。五福心脑清可减轻多发性脑梗死大鼠脑组织形态学改变。结论 五福心脑清对多发性脑梗死性痴呆大鼠模型具有保护作用。【关键词】 五福心脑清；多发脑梗死性痴呆；SOD；MDA
Effect of WuFuXinNaoQing on cerebral multi-infarction dementia rat model
ZHANG Mi-xia, ZHANG Yan-jun,HUANG Huai-peng,et alTianjin University of Traditional Chinese Medicine, Tianjin 3000193,China
【Abstract】 Objective To study the protective effects of WU FU XIN NAO QING on cerebral multi-infarction dementia(MID) rat model Methods The multi-infarction dementia model was induced by injecting cruor embolus of the same kind rats into the internal carotid artery The SOD and MDA of serum was measured And the pathology of brain was observed Results Compared with the control group,the content of SOD in serum of the multi-infarction dementia rats was reduced,the content of MDA was increasedFuFangDanShenDiWan and WuFuXinNaoQing can reverse the content of them Moreover, the morphology demonstrated that FuFangDanShenDiWan and WuFuXinNaoQing can decrease the pathological destroy of the brain Conclusion The results of this study suggest that WuFuXin NaoQing have protective effects on multi-infarction dementia rat model ......
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