摘要：目的:比较利培酮与氟哌啶醇治疗小儿多发性抽动(Tourette syndrome，TS)的疗效与安全性。方法: 将152例TS患儿随机分为2组，分别予利培酮和氟哌啶醇以相同的给药方法和剂量治疗，应用《耶鲁抽动程度综合量表》评价2组治疗效果与副作用。结果: 利培酮组在疗效、药物副作用等方面明显优于氟哌啶醇组(P<0.05)。结论: 利培酮治疗TS疗效较氟哌啶醇好，且副作用明显减少，患儿依从性好，具有较好的前景。

     关键词：小儿多发性抽动症；利培酮；氟哌啶醇

    Clinical Study of Risperidone and Haloperidol in Treating Tourette Syndrome

    HUANG Hai-zhong,et al

    (The People's Hospital of Huizhou, Guangdong Huizhou 516002, China)

    Abstract: Objective: To compare the efficacy and safety of risperidone and haloperidol in treating Tourette syndrome(TS). Method: A total of 152 patients with Tourette Syndrome were randomly divided into two groups treatment with haloperidol and risperidone. The efficacy was measured by the Yale globaltic severity scale. Result: Riperidone is more effective and has less side effects than haloperidol in the treatment of TS,significant difference was found between the two groups(P<0.05). Conclusion: The results suggest that riperidone is more effective and has less side effects than haloperidol in the treatment of TS. ......