老年高血压病患者动态脉压与颈动脉粥样硬化相关性研究
高血压病;,动态脉压;颈动脉;动脉粥样硬化,,高血压病;,动态脉压;颈动脉;动脉粥样硬化,摘要,关键词,1资料与方法,2结果,3讨论,参考文献
摘要: 目的： 探讨老年原发性高血压患者动态脉压与颈动脉粥样硬化间的关系。方法：根据动态全天平均脉压将95例原发性高血压患者分为两组。所有病人均经超声检测颈总动脉、颈内动脉和颈动脉分叉处的内膜中层厚度、血管内径，并计算斑块发生率。以颈总动脉最大内膜中层厚度(IMTmax)作为评价颈动脉粥样硬化程度的指标。结果：脉压>60 mmHg 的患者颈总动脉内径、颈总动脉最大内膜中层厚度、颈动脉斑块发生率明显高于脉压为40~60 mmHg患者(P<0.05)。Pearson相关分析显示，平均脉压、平均收缩压及病程与颈总动脉最大内膜中层厚度呈明显正相关(r分别为0.410、0.217、0.247，P<0.05),而平均舒张压与颈总动脉最大内膜中层厚度呈负相关(r=-0.404, P<0.01)。结论： 老年原发性高血压患者脉压差与颈动脉粥样硬化斑块和内中膜厚度相关，脉压差可能参与动脉粥样硬化的形成和发展。关键词: 高血压病; 动态脉压;颈动脉;动脉粥样硬化
The association of ambulatory pulse pressure with carotid artery atherosclerosis in the eldly with hypertension
LAI Hongmei, ZHANG Xiangyang
(Department of Hypertension, First Affiliated Hospital, Xinjiang Medical University,Urumqi 830054, China)
Abstract: Objective: To investigate the relationship between ambulatory pulse pressure (PP) and carotid artery atherosclerosis in elderly hypertensive patients. Methods: Totally ninetyfive elderly patients with essential hypertension, were tested with the color Doppler ultrasounography to perform the carotid artery ultrasonic examination to measure the intimamedia thickness(IMT), lumen diameter and plaque of common carotid artery of the two sides. Maximal intimamedia thickness(IMTmax) was used as the index of carotid atherosclerosis severity. Results: All the ninetyfive patients were involved in the analysis of results: the IMTmax and lumen diameter in the group A (PP>60 mmHg) were obviously higher than those in the group B (PP<60 mmHg). the incidence rate of carotid artery plaque was higher in group A than that in Group B. Conclusion: The pulse pressure is related to carotid artery plaque and the carotid intimamedia thickness. Atherosclerosis is the cause of elevated pulse pressure, elevated pulse pressure may be involved in forming and developing of atherosclerosis. ......
您现在查看是摘要页，全文长 9885 字符。