摘要：目的：观察优思弗联合甘利欣胶囊治疗慢性乙型肝炎的疗效。方法:87例慢性乙型肝炎患者均为抗病毒治疗失败或肝功能长期异常者,随机分为治疗组(47例)和对照组(40例),分别给予甘利欣胶囊联合优思弗胶囊和复方甘草酸苷+维生素C治疗,疗程均为8wk。结果:治疗组在肝功能、免疫功能改善方面优于对照组(P<0.05);治疗组与对照组总有效率分别为89.4%、67.5%(P<0.01)。结论:甘利欣联合优思弗治疗抗病毒失败或肝功能长期异常者有效。

    关键词： 慢性乙型肝炎; 甘利欣胶囊; 优思弗胶囊; 疗效

    Observing the Effect of Glycyrrhizinate Comownd Ursodeoxycholi acid on Treating Chronic Hepatits B

    TAN Xiao-yun， LIU Xing-feng， CHEN Xing-hao

    (Yuebei Second People's Hospital, Guangdong Shaoguan 512028, China)

    Abstract: Objective: To observe the therapeutic effect of compound glycyrrhizin combining ursodeoxy-cholic acid in the treatment of chronic hepatitis B.Method: 87 patients with chronic hepatitis B were enrolled to,on whom, the anti-viral therapy proved to be ineffective and who suffered a long- term abnormal liver functions, of the total ,47 were randomly assignesd to receive compound glycyrrhizin plus ursodeoxycholic acid(treatment,group), and 40 to receive compound glycyrrhizin plus vitamin C(control group). Course of treatment for both groups was 8 weeks. Result: As compared with the control group, the liver function and immune function for the treatment group had a better amelioration(P<0.05) );the total effective group, the liver function and immune control group were 89.4% and 67.5%(P<0.01), respectively. Conclusion: Compound glycyrrhizin plus ursodeoxycholi acid is effective in treatment of chronic hepatitis B cases when anti-viral therapy is ineffective and whose liver function are abnormal for a long time. ......