电针足三里穴抗大鼠应激性胃黏膜损伤作用与NTS内受体的关系
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黄碧兰, 王秋桂, 余良主, 唐 琼, 丁洁琼
NTS;受体阻断剂;应激性胃黏膜损伤黄碧兰,王秋桂,余良主,唐琼,丁洁琼.EA足三里穴抗大鼠应激性胃黏膜损伤作用与NTS内受体关系的研究. 世界华人消化杂志2006;14(24)2444-
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黄碧兰, 余良主, 唐琼, 丁洁琼, 咸宁学院医学院生理学教研室 湖北省咸宁市 437100
王秋桂, 咸宁学院医学院组织胚胎学教研室 湖北省咸宁市 437100院科研基金资助项目, No. KY0539
通讯作者: 黄碧兰, 437100, 湖北省咸宁市, 咸宁学院医学院生理学教研室. huangbilan@etang.com
电话:0715-8175615
收稿日期: 2006-05-13 接受日期: 2006-07-10
Effect of electroacupuncturing Zusanli point on stress-induced gastric mucosal injury and and its relationship with receptors in nucleus tractus solitarius
Bi-Lan Huang, Qiu-Gui Wang, Liang-Zhu Yu, Qiong Tang, Jie-Qiong Ding
Bi-Lan Huang, Liang-Zhu Yu, Qiong-Tang, Jie-Qiong Ding, Department of Physiology, School of Medicine, Xianning College, Xianning 437100, Hubei Province, China
Qiu-Gui Wang, Department of Histology and Embryology, School of Medicine, Xianning College, Xianning 437100, Hubei Province, China
Supported by the Science Research Foundation of Xianning College, No. KY0539
Correspondence to: Bi-Lan Huang, Department of Physiology, School of Medicine, Xianning College, Xianning 437100, Hubei Province, China. huangbilan@etang.com
Received: 2006-05-13Accepted: 2006-07-10
Abstract
AIM:To investigate the relationship between the effect of electroacupuncturing (EA) Zusanli point on the stress-induced gastric mucosal injury and the receptors in nucleus tractus solitarius (NTS) in rats.
METHODS:Fifty-six male SD rats were randomly divided into 8 groups, and gastric ulcer was induced in all the rats by constraint cold method. Except those in model group, the rats were treated with EA, NS+EA, prazisin+EA, yohimbine+EA, propranolol+EA, atropine+EA, and naloxone+EA, respectively. The ulcer indexes were observed after microinjection of various receptor antagonists into NTS.
RESULTS: In comparison with that in model group, the UI was significantly reduced in NS+EA or EA group (26.3 ± 3.5, 25.4 ± 3.1 vs37.5 ± 4.2, t = 5.42, t = 6.13, both P < 0.01). In comparison with that NS+EA stree group, the UI was markedly increased in prazisin+EA or tropine+EA group (34 ......
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