[摘要] 目的 检测微血管密度(MVD)在不同分化程度的宫颈鳞状细胞癌的表达状况，从而揭示该指标与宫颈鳞癌病理分化的关系，评估微血管密度对不同分化程度的宫颈鳞癌的诊断、预后判断价值。 方法 选取宫颈鳞癌标本60例(其中低分化鳞癌28例、中高分化鳞癌32例)，采用免疫组化S-P法，分别检测上述两组病理标本微血管密度。 结果 微血管密度在低分化宫颈鳞癌、中高分化宫颈鳞癌中的记数分别为39.93±9.38、24.50±7.79, 差异有非常显著性(P<0.01)。 结论 微血管密度与宫颈鳞癌的分化程度密切相关,随着宫颈鳞癌分化程度降低,恶性程度增高,微血管密度增加，微血管密度检测可作为判断宫颈鳞癌恶性程度、浸润性及预后的参考指标。

    [关键词] 宫颈鳞癌；微血管密度；免疫组织化学

    Expression of MVD in squamous carcinoma of cervix

    MA Yu-fang,SONG Shi-mao,YI Jian-hua,el al. Department of Oncology,Taihe Hospital of Yunyang Medical College,Shiyan 442000,China

    [Abstract] Objective To investigate the correlation between the expression of MVD values and pathological grade of squamous cell carcinoma of cervix.Methods Sixty patients with squamous cell carcinoma of cervix treated from 1997 to 1999 were，and the expression of MVD values were examined on the paraffin specimens by using routine SP immunohistochemical method.Results The rates of MVD were 39.93± 9.38 and 24.50±7.79 respectively.There was a high significance(P<0.01)and the more MVD counted ......