脑梗死；血浆组织型纤溶酶原激活剂；血管性血友病因子；纤维连接

急性脑梗死患者细胞因子测定及其临床意义

http://www.100md.com 《吉林医药医学学报》 2006年第3期

脑梗死；血浆组织型纤溶酶原激活剂；血管性血友病因子；纤维连接蛋白；内皮素；6酮前列腺素,1对象与方法,2结果,3讨论,参考文献：

     摘要：目的探讨急性脑梗死患者血浆中血栓与止血检验相关标记物含量变化及其与临床之间的关系。方法测定急性脑梗死患者53例血浆组织型纤溶酶原激活剂(tPA)、血管性血友病因子(vWF)、纤维连接蛋白(Fn)、内皮素(ET)、6酮前列腺素(6KPGF1α)含量，并与正常对照组比较。结果急性脑梗死患者血浆中tPA含量较正常对照组低(P<0.01) ； vWF、Fn、ET、6KPGF1α含量较正常对照组高(P<0.01) 。结论血浆中tPA、vWF、Fn、ET、6KPGF1α含量的变化与急性脑梗死的发病有关。

    关键词：脑梗死；血浆组织型纤溶酶原激活剂；血管性血友病因子；纤维连接蛋白；内皮素；6酮前列腺素

    Cytokine determination and its clinical significance in acute cerebral infarction patient

    HUANG Qinhua (Pingguo People's Hospital, Pingguo, Guangxi Province, 531400, China)

    Abstract:Objective To study changes of content that thrombus get along with hemostasia test correlation marker in plasm of acute cerebral infarction patients, and theirs relation of clinic. Methods Content of tissuetype plasminogen activator(tPA), von Willebrand disease factor (vWF), fibronectin (Fn), endothelins(ET), 6ketonprostaglandin (6KPGF1α) were estimated in 53 acute cerebral infarction patients, which were compared with normal control group. Results Content of tPA in plasm of acute cerebral infarction patients was lower than its in normal control group(P<0.01); Content of vWF, Fn, ET, 6KPGF1αwas higher than its in normal control group(P<0.01). Conclusion Changes of tPA, vWF, Fn, ET, 6KPGF1αin plasm relate greatly with episode of acute cerebral infarction. ......

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