急性脑梗死患者血清中IL1β及IL6水平变化的研究
脑梗死;IL1;IL6,,脑梗死;IL1;IL6,1资料与方法,2结果,3讨论,参考文献
【摘要】 目的:研究急性脑梗死患者血清中IL1β及IL6含量的变化。方法:采用病例对照的研究方法,选择急性脑梗死患者45例为病例组,健康体检者40例为对照组,用酶联免疫吸附法定量检测血清中IL1β及IL6的含量。结果:病例组血清中IL1β、及IL6的含量平均值分别是248±51pg/ml和232±84pg/ml;对照组分别是150±46pg/ml和195±99,两组比较有统计学意义。结论:急性脑梗死患者血清中IL1β及IL6的含量明显增高,后者是导致急性脑梗死的发展机制之一。【关键词】 脑梗死;IL1;IL6
Study on the Changes of IL6 and IL1β Levels in the Serum of Acute Cerebral Infarction Patients
YU Aimei, ZOU Yuan
Department of Neurology, the First Affiliated Hospital,
Hebei North University, Zhangjiakou, 075000, Hebei China
【ABSTRACT】 Objective: To study the changes of IL6 and IL1β levels in the serum of acute cerebral infarction patients.Methods: By the casecontrol study, 45 cases with acute cerebral infarction (patients group) and 40 health controls (control group) were selected, then test IL6 with ELISA.Results:The average values of IL1β and IL6 were 248±51pg/ml and 232±84pg/ml in patient group; the average values of IL1β and IL6 were 150±46pg/ml and 177±91 pg/ml in control group. There was statistical difference between patient group and control group.Conclusion:The average values of IL1β and IL6 were higher in patient group than that of control group, and these elements might bring about acute cerebral infarction. ......
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