胰腺炎急性；一氧化氮；动物_实验_

急性胰腺炎鼠血清一氧化氮的测定及意义

http://www.100md.com 《广东药学院学报》 1999年第3期

胰腺炎急性；一氧化氮；动物,实验,,胰腺炎急性；一氧化氮；动物，实验,1材料和方法,2结果,3讨论,4参考文献

     摘要目的：检测急性胰腺炎(AP)鼠血清NO浓度并讨论其意义。方法：Wistar大鼠56只随机分为实验组(30只)和对照组(26只)。经胰胆管注射牛磺胆酸钠诱发大鼠急性胰腺炎模型。术后6 h、12 h测定各组鼠血清NO浓度。结果：AP鼠血清NO水平明显升高(P<0.001)。结论：NO参与了AP的病理生理过程。

    关键词：胰腺炎急性；一氧化氮；动物，实验

    Determination of serum nitric oxide in rats with acute pancreatitis and its significance

    Wang Gengshu，Liu Weifang，Li Mingyi

    (Hepatobikiary Department of Affikiated Hospitak of Guangdong Medicak Cokkege.Zhan jiang 524001)

    Abstract Objective：To detect serum nitric oxide of rats with acute pancreatitis (AP)and discuss its significance.Methods：Fiftysix Wistar rats were divided randomky into AP Group (n＝30) and controk Group(n＝26).AP was induced by injection of 4.5% sodium taurochokate into the pancreatobikiary duct.Serum NO was detected at 6 and 12 hours after operation.Resukts： Serum NO of rats with AP was significantky higher than that of rats in controk Group (P<0.001).Conckusion： Nitric oxide might have a roke in pathogenesis of AP.

    Key words：pancreatitis ......

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