氯丙嗪、利培酮治疗精神分裂症致糖耐量变化的研究
2小时糖耐量,精神分裂症,抗精神病药物,,2小时糖耐量,精神分裂症,抗精神病药物,1对象与方法,2结果,3讨论,参考文献
【摘要】 目的 研究利培酮和氯丙嗪短期治疗精神分裂症患者2小时糖耐量变化特点。方法 随机选择198例未曾治疗或停药3个月以上的精神分裂症患者，分别接受利培酮、氯丙嗪治疗。在入院时，治疗1、2、3、6个月后检测2hPG。结果 氯丙嗪治疗3月后2hPG值明显增高，利培酮组增高不明显；≥40岁组2hPG明显高于<40岁组；同年龄组比较，治疗6个月，20岁以上各组2hPG浓度明显高于治疗前。结论 氯丙嗪比利培酮更易引起2hPG值增高，治疗3个月检测2hPG值有助于判断精神病患者伴发糖尿病的风险。【关键词】 2小时糖耐量 精神分裂症 抗精神病药物
Study on Influence of the Short-term Therapy by Chlorpromazine or Risperidal on 2hPG
Wang Tao,et al.
(Mental Health Centre,New District of Pudong,Shanghai 200122)
【Abstract】 Objective To study the 2hPG about antipsychotic in the short-term therapy.Methods 198 inpatients with Schizophrenia were untreated or stopped antipsychotics beyond 3 months,were randomly chosen.They were treated separately by chlorpromazine or risperidal and detected the 2hPG，before treatment,after one,two,three,and six months treatment.Results The 2hPG after three months in chlorpromazine group obviously raised compared with previous treatment ......
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