神经细丝酸性蛋白在泪腺腺样囊性癌中的表达及意义
泪腺腺样囊性癌；神经细丝酸性蛋白；嗜神经性侵袭性；雪旺细胞分化,,],泪腺腺样囊性癌；神经细丝酸性蛋白；嗜神经性侵袭性；雪旺细胞分化,1材料与方法
[摘要] 目的 研究雪旺细胞标记物神经细丝酸性蛋白(GFAP)在腺样囊性癌有嗜神经性侵袭组与无嗜神经性侵袭组中的表达的差异，旨在进一步探明泪腺腺样囊性癌嗜神经性侵袭性生长的机制。方法 应用免疫组化S-P法检测GFAP在28例腺样囊性癌中的表达情况。结果 有嗜神经侵袭性生长组中的GFAP阳性表达率较无嗜神经侵袭性生长组呈升高趋势(P<0.05)。结论 泪腺腺样囊性癌的嗜神经性侵袭特性可能与肿瘤细胞中存在着雪旺细胞分化有关。[关键词] 泪腺腺样囊性癌；神经细丝酸性蛋白；嗜神经性侵袭性；雪旺细胞分化
Expression and significance of GFAP in lacrimal adenoid cystic carcinoma
WANG Leifeng,ZHU Sufang,HEI Yan,et al.The Second Hospital of Beijing CAPF,Beijing 100037,China
[Abstract] Objective To investigate the expression of Schwanns cell markers GFAP in lacrimal gland adenoid cystic carcinoma.
Methods S-P(Streptavidin/Peroxidase) immunohistochemical staining was used to determine the expression of GFAP in 28 lacrimal gland adenoid cystic carcinoma.
Results GFAP in norneural invasion group and neural invasion group was 0 and (2.07±3.01),respectively,in lacrimal gland adenoid cystic carcinoma (P<0.05). ......
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