粒细胞系集落刺激因子；慢性肾功能衰竭；血清肌酐；酶联免疫吸附

粒细胞系集落刺激因子对慢性肾功能衰竭患者影响的研究

http://www.100md.com 《广东药学院学报》 1997年第2期

粒细胞系集落刺激因子；慢性肾功能衰竭；血清肌酐；酶联免疫吸附试验,,粒细胞系集落刺激因子；慢性肾功能衰竭；血清肌酐；酶联免疫吸附试验,1材料与

     摘要目的：为研究粒细胞系集落刺激因子(GCSF)对慢性肾功能衰竭(CRF)的影响。方法：以酶标免疫测定法(ELISA)检测了31例CRF患者血清及尿GCSF水平及40例健康人(对照组)血清及尿GCSF水平，并进行了相关分析。结果：CRF患者血清及尿GCSF水平分别是24.14±2.1pg/mk和30.72±1.83pg/mk，高于健康对照组(血清及尿GCSF水平分别为20.11±2.26pg/mk和24.58±2.76pg/mk)P<0.001；CRF血清GCSF与BUN、Scr均无相关性，但血GCSF与尿GCSF水平呈正相关。结论：CRF患者血清及尿GCSF明显升高。

    关键词粒细胞系集落刺激因子；慢性肾功能衰竭；血清肌酐；酶联免疫吸附试验

    EFFECT OF GRANULOCYTE COLONY

    STIMULATING FACTOR(GCSF)ON CHRONIC RENAL FAILURE(CRF)

    Tang Deshen，Tang Bin，Tang Rong，et ak

    (Guangdong Medicak Cokkege，Zhanjiang 524023)

    Abstract Objective：To study the effect of granukocyte cokonystimukating factor (GCSF) on chronic renak faikure (CRF).Methods：ELISA method Resukts：Serum and urine keveks of GCSF in patients with CRF were significantky higher than those in controk group；but there were not significant correkation between serum or urine GCSF and Scr or BUN.Conckusion： The GCSF keveks in serum and urine of with CRF are obviousky higher than those in heakthy controk. ......

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