摘要:目的 了解抗疟药包装对疟疾病人治疗干预的效果。 方法 实验区接受起泡包装的磷酸氯喹和磷酸伯喹单人份包装，在起泡包装背面标示药名和剂量，并配相应小盒，小盒正反面及二侧标有作用与用途、用法与剂量等;对照区接受普通纸包装或纸袋包装。比较现症病人和休根病人对起泡包装和纸袋分发的服药依从性，并进行成本-效益分析。 结果 实验区疟疾病人全程足量治疗率为97.6%，对照区全程足量治疗率为77.08%，实验区疟疾病人服药依从性明显高于对照区(χ 2 =19.63，P<0.01);实验区春季休根治疗疟史病人依从性明显高于对照区(χ 2 =33.60，P<0.01)，并能有效减少防治经费开支。 结论 起泡包装抗疟药能提高疟疾病人的服药依从性，且能较好地节省经费，值得在疟防工作中推广应用。

    关键词:疟疾;依从性;药物包装

    Observation on the therapeutic effect of antimalarial drugs after changed packing.

    WANG Wei-ming，CAO Jun，ZHOU Hua-yun，et al.

    (Jiangsu Provincial Institute of Schistosomiasis，Wuxi214064，Jiangsu，P.R.China)

    Abstract:Objective To understand the intervention effects of improved antimalarial drugs packaging treatment on malarial pa-tients. Methods The experimental group received medication in two separate blister packs，chloroquine and primaquine and each blister contained drug name，dose and packetwith instruction of use.The control group received medication in the normal paper enve-lope.Compliance of patients in both2groups was observed and cost of treatment in the two groups was compared. Results 97.6%of patients in experimental group were treated with a full course and completed dosage ......