【摘要】 目的 探讨尼莫地平与银杏叶注射剂合用治疗急性脑梗死的临床疗效。方法 将89例急性脑梗死病人随机分成尼莫地平组(29例，只用尼莫地平)，银杏叶组(30例，单用银杏叶注射剂)及两药合用组(30例)。尼莫地平的用法为尼莫地平口服，每次30mg，每日3次。银杏叶注射剂的用法为20ml加入到5%葡萄糖氯化钠溶液或0.9%氯化钠溶液250ml中静脉滴注；每日1次。3组均治疗30天。其他治疗两组相同。治疗前后分别进行神经功能缺损评分。检查血常规、肝功能、肾功能、凝血功能。结果 两组合用显效率66.67%，有效率93.33%，均显著高于尼莫地平组和银杏叶组(P<0.01)，未发现有严重的肝、肾功能损害及出血不良反应。结论 尼莫地平与银杏叶注射剂合用治疗急性脑梗死安全有效，疗效优于其中一种药物者。

    【关键词】 尼莫地平；银杏叶注射剂；脑梗死；治疗效果；不良反应

    Effect of nimodipine combined with YinXingYe on the treatment of acute cerebral infarction

    WU Li-sha. Department of Internal Medicine,The People's Hospital of Linzhi 860000,China

    【Abstract】 Objective To evaluate the clinical efficacy of YinXingYe combined with nimodipine on the treatment of acute cerebral infarction. Methods Eighty nine patients were randomly divided into three groups:Twenty nine patients were treated with nimodipine 30mg po tid,thirty patients were treated only with 20ml YinXingYe once daily by intravenous drip.Thirty patents were treated with YinXingYe and nimodipine.Three groups were treated for 30days.Impaired neurological function score,blood routine,liver and kidney function,blood coagulation were examined before and after treatment. Results Significant effective rate and effective rate were 66.67% and 93.33% respectively in those patients treated with YinXingYe combined with nimodipine,significantly higher than that in the other two guoups (P<0.05).No severe adverse reactions after treatment were found. Conclusion YinXingYe combined with nimodipine is an effeetive and safe regimen for the treatment of acut cerebral infarction. ......