【摘要】 目的 观察桑黄对肿瘤的抑制作用及对机体免疫功能的影响。 方法 以小鼠艾氏腹水癌的生命延长率评价桑黄的抗肿瘤作用，以炭末廓清实验观察荷瘤小鼠非特异性免疫功能，以ELISA法测定荷瘤小鼠血清IL-2浓度。结果 桑黄对EAC荷瘤小鼠的生存时间有延长作用，对荷瘤小鼠血清IL-2浓度有提高作用，对荷瘤小鼠非特异性免疫功能无明显影响。结论 中药桑黄对荷瘤小鼠具有一定的抗肿瘤能力，作用的强度和作用机制的深度还有待进一步研究。

    【关键词】 桑黄；抗肿瘤；免疫

    Study of Phellinus linteus about anti-tumor activity and enhancing immune effect

    ZHANG Jin, LI Bao-hua, WANG Yong-quan, et al. Pharmacologic Center, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021,China

    【Abstract】 Objective To study the anti-tumor activity and enhancing immune effect of Phellinus linteus.Methods The anti-tumor activity of Phellinus linteus was estimated by the longevity of EAC mice,the immune effect of tumorous mice was tested by the experiment of carbon particle expurgation and the IL-2 concentration in serum of tumorous mice was determined by ELISA.Results Phellinus linteus can prolong EAC mouse’s life and can increase the IL-2 concentration in serum of tumorous mouse but can’t affect the immune effect of tumorous mouse.Conclusion Chinese hurb Phellinus linteus possess some antitumor power for tumor-loaded mice,but further research is needed. ......