丹参对急性胰腺炎患者血浆内皮素和P-选择素变化的影响
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周晓娜, 胡 静
胰腺炎;内皮素;P-选择素;丹参,周晓娜,胡静,通讯作者:,InfluenceofSalviamiltiorrhizaonthechangesofplasmaendothelinandP-selectininpatientswithacut
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周晓娜, 胡静, 河北医科大学附属石家庄市第一医院消化内科 河北省石家庄市 050017石家庄市科技发展项目, No. 051201443
通讯作者: 周晓娜, 050017, 河北省石家庄市范西路36号, 河北医科大学附属石家庄市第一医院消化内科. hbzhj@163.net
电话: 0311-86919593
收稿日期: 2006-09-09 接受日期: 2006-10-11
Influence of Salvia miltiorrhiza on the changes of plasma endothelin and P-selectin in patients with acute pancreatitis
Xiao-Na Zhou, Jing Hu
Xiao-Na Zhou, Jing Hu,Department of Gastroenterology, the First Hospital of Shijiazhuang City, Hebei Medical University, Shijiazhuang 050017, Hebei Province, China
Supported bythe Science and Technology Development Foundation of Shijiazhuang City, No. 051201443
Correspondence to:Xiao-Na Zhou, Department of Gastroenterology, the First Hospital of Shijiazhuang City, Hebei Medical University, Shijiazhuang 050017, Hebei Province, China. hbzhj@163.net
Received:2006-09-09 Accepted:2006-10-11
Abstract
AIM: To explore the changes of plasma endothelin and P-selectin as well as the effects of Salvia miltiorrhiza (SM) in patients with acute pancreatitis (AP).
METHODS: A total of 82 patients with acute pancreatitis were divided into group A (n = 40) and B (n = 42), treated with general method and SM, respectively. Anther 20 normal individuals were used as normal controls. The levels of plasma endothelin (ET) and P-selectin were measured by radioimmunoassay.
RESULTS: The levels of ET and P-selectin in patients with severe acute pancreatitis (SAP) were significantly higher than those in the cases with mild acute pancreatitis (MAP) and normal controls (ET: 147.56 ± 10.65 ng/L vs 85.13 ± 9.47, 52.27 ± 6.23 ng/L, P < 0.01; P-selectin: 85 ......
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