小鼠对乙肝病毒小基因嵌合DNA疫苗免疫应答
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张建军, 杨向东, 史小玲, 袁志平, 王 超
嵌合DNA疫苗;小基因;CD80分子;乙型肝炎病毒,张建军,张建军,杨向东,史小玲,袁志平,王超,通讯作者:,ImmunologicresponsetoahepatitisBvirussmallgenechimericDNAvaccin
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张建军, 泸州医学院附属医院感染病科 四川省泸州市 646000
张建军, 杨向东, 泸州医学院附属医院分子医学中心实验室 四川省泸州市 646000
史小玲, 泸州医学院附属医院传染与免疫研究室 四川省泸州市 646000
袁志平, 宜宾市第二人民医院肿瘤科 四川省宜宾市 644000
王超, 山东省疾病控制中心 山东省济南市 2500014
四川省卫生厅资助项目, No. 000111
通讯作者: 张建军, 646000, 四川省泸州市, 泸州医学院附属医院感染病科. zhangjianjun2535@163.com
收稿日期: 2006-09-21 接受日期: 2006-10-11
Immunologic response to a hepatitis B virus small gene chimeric DNA vaccine in mice
Jian-Jun Zhang, Xiang-Dong Yang, Xiao-Ling Shi, Zhi-Ping Yuan, Chao Wang
Jian-Jun Zhang,Department of Infectious Diseases, the Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
Jian-Jun Zhang, Xiang-Dong Yang,Central Laboratory for Molecular Medicine, the Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China
Xiao-Ling Shi,Department of Infectious Diseases and Immunology, the Affiliated Hospital of Luzhou Medical College, Luzhou 46000, Sichuan Province, China
Zhi-Ping Yuan,Department of Oncology, the Second People’s Hospital of Yibin City, Yibin 644000, Sichuan Province, China
Chao Wang,Shandong Provincial Center for Disease Provention and Control, Ji’nan 2500014, Shandong Province, China
Supported bySichuan Provincial Bureau of Health, No. 000111
Correspondence to:Jian-Jun Zhang, Department of Infectious Diseases, the Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China. zhangjianjun2535@163.com
Received:2006-09-21 Accepted:2006-10-11
Abstract
AIM: To investigate the immunologic response to pcHBV-CD80, a hepatitis B virus (HBV) small gene chimeric DNA vaccine containing CD80, in mice ......
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