慢乙肝母婴传播阻断和治疗策略的建议
http://www.100md.com
郑鹏远, 唐芙爱, 卢高峰, 白经修
慢性乙型肝炎;母婴传播;免疫治疗,郑鹏远,唐芙爱,卢高峰,白经修,郑鹏远,通讯作者:,PreventionofverticaltransmissionandtreatmentofchronichepatitisB,Peng-YuanZheng,Fu-A
 |
| 第3页 |
 |
| 第1页 |
参见附件(963KB，6页)。
郑鹏远, 唐芙爱, 卢高峰, 白经修, 郑州大学第二附属医院消化科 河南省郑州市 450014
郑鹏远, 郑州大学第二附属医院消化科教授, 博士生导师, 主要从事幽门螺杆菌及慢乙肝研究.
河南省卫生厅医学创新人才工程项目, No. 2004-45
河南省科技厅科技攻关项目, No. 0324410006
通讯作者: 郑鹏远, 450014, 河南省郑州市经八路2号, 郑州大学第二附属医院消化科. medp7123@yahoo.com
电话: 0371-65261035
收稿日期: 2006-10-18 接受日期: 2006-11-16
Prevention of vertical transmission and treatment of chronic hepatitis B
Peng-Yuan Zheng, Fu-Ai Tang, Gao-Feng Lu, Jing-Xiu Bai
Peng-Yuan Zheng, Fu-Ai Tang, Gao-Feng Lu, Jing-Xiu Bai,Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, He’nan Province, China
Supported bythe Innovation Talent Project from Health Department of He’nan Province, No. 2004-45, and the Key Item from Science and Technology Department of He’nan Province, No. 0324410006
Correspondence to:Peng-Yuan Zheng, Department of Gastroenterology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, He’nan Province, China. medp7123@yahoo.com
Received:2006-10-18 Accepted: 2006-11-16
Abstract
Vertical transmission is the main path of hepatitis B virus (HBV) infection in patients with chronic hepatitis B (CHB). According to the development history of embryo and the possible mechanism of vertical transmission, it’s supposed that the effective method to prevent vertical transmission should be immunoprophylaxis in both mother and baby. Pregnant woman with positive HBsAg should receive monthly injection of 200 IU hepatitis B immunoglobulin (HBIg, or 400 IU once if HBV DNA is positive) from the 16th week after pregnancy (at from the 20th week). The newborn child should receive combined immunization (active/passive), namely injection of 200 IU HBIg within 24 hours (better within 6 hours) after birth, and one more repeat after 2 weeks. HBV vaccination should be carried out at the same time in order to acquire the best protection result ......
您现在查看是摘要介绍页，详见PDF附件(963KB，6页)。