平消胶囊;_Ⅰ～Ⅱa期非小细胞肺癌____

平消胶囊对手术后Ⅰ～Ⅱa期非小细胞肺癌的治疗分析

http://www.100md.com 《河北北方学院学报》 2006年第4期

平消胶囊;,Ⅰ～Ⅱa期非小细胞肺癌,,平消胶囊;,Ⅰ～Ⅱa期非小细胞肺癌,1资料和方法,2结果,3讨论,参考文献

     【摘要】目的: 观察平消胶囊对手术后Ⅰ～Ⅱa期非小细胞肺癌的1、3年生存率，免疫功能及生存质量的影响。方法: 全部患者均经病理证实的非小细胞肺癌。根据临床和术后病理确定为Ⅰ～Ⅱa期，Karnofsky评分≥70分，年龄在35～75岁。治疗组术后两周给予平消胶囊治疗，一次4～5粒，3次/d，90d为一疗程，对照组术后不给予任何治疗。治疗结束后对两组病人的1、3年生存率，免疫功能及生存质量进行评估。结果: 治疗组1、3年生存率分别为955%、665%；对照组为940%、645%。两组1、3年生存率差异无显著性(P>005)，治疗组外周血T细胞亚群、T淋巴细胞的比值明显高于对照组(P<005)。生存质量(生活质量调查、体重、卡氏评分)明显高于对照组(P<005)。结论: 平消胶囊具有增加患者免疫力及提高生存质量的作用，但对术后Ⅰ～Ⅱa期非小细胞肺癌的生存率(1、3年生存率)无明显影响。

    【关键词】平消胶囊; Ⅰ～Ⅱa期非小细胞肺癌

    Analysis on the Treatment with Pingxiao Capsule for Ⅰ～Ⅱa NSCLC

    ZHANG Zhenming, ZHU Decheng, DONG Yuehua

    The First Affiliated Hospital,Hebei North University,Zhangjiakou,075000,Hebei, China

    【ABSTRACT】 Objective: To investigate the survival rate in one and three years,the immunity and living quality while the Ⅰ～Ⅱa NSCLC patients were treated with Pingxiao Capsule after operation.Methods:The patients confirmed suffering from non small cell lung cancer(NSCLC) were diagnosed being in the Ⅰ～Ⅱa period,Karnofsky≥70,35~70 years old (including 35 and 75).The group was treated with Pingxiao Capsule,4~5 capsules pertime,three times a day,taking 90 days as treating course,but the control group didnt receive any treatment.After the treatment ended,the survival rate, immunity and living quality were evaluated.Results:For the treated group,the survival rates for one and three years were 955% and 665% separately.For the control group,the rates of that were 940% and 645%.There is no significant differece between the two groups(P>005).The specific data of outside Tcell submass and limphcell in the treated group was higher than that of the control group(P<005).The treated groups living quality(living quality form of questionnaire,weight,calculative mark) was higher than that of the control group(P<005).Conclusion:Pingxiao Capsule has the function to improve patients immunity and living quality.But there is no remarkable affect on survival rate of the patients suffering from nonsmall cell lung cancer after operation. ......

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