慢性肝炎患者血清IL6、IL8、IL10的变化及其临床意义
慢性肝炎;,白细胞介素6;白细胞介素8;白细胞介素,,慢性肝炎;,白细胞介素6;白细胞介素8;白细胞介素,1材料与方法
摘要:目的 探讨慢性肝炎患者血清白细胞介素6 (IL6)、白细胞介素8(IL8)和白细胞介素10(IL10)在慢性肝炎发展过程中的含量变化及其临床意义。方法 用放射免疫分析法检测80例慢性肝炎患者和40例正常对照组血清IL6、IL8和IL10的水平。结果 各组慢性肝炎患者血清IL6和IL8含量高于正常对照组,差异有统计学意义(P<0.05);IL10低于正常对照组,差异有统计学意义(P<0.01)。IL6、IL8和IL10水平的变化与慢性肝炎病变程度密切相关。结论 细胞因子IL6、IL8和IL10在慢性肝炎发展过程中相互作用,联合检测其水平的变化对探讨慢性肝炎的诊断和预后具有重要意义。关键词:慢性肝炎; 白细胞介素6;白细胞介素8;白细胞介素
Study on the Changes of Serum IL6,IL8 and IL10 Levels in Patients with Chronic Hepatitis and its Clinical Significance
DIAO Muyan
(Shenzhen Entryexit Inspection and Quarantine,Shenzhen Guangdong 518045,China)
ABSTRACT:Objective To investigate the changes of serum IL6,IL8 and IL10 levels in patients with chronic hepatitis of various types and explore its clinical significance.Methods Serum IL6,IL8 and IL10 levels were measured with RIA in 80 patients with chronic hepatitis and 40 controls.Results Serum IL6 and IL8 levels were significantly higher in patients with chronic hepatitis than those in controls(P<0.05),but serum IL10 level was significantly lower in the patients(P<0.01).Serum IL6 ......
您现在查看是摘要页,全文长 5114 字符。