铅；血清酶；逆向变化_____铅；血清酶；逆向变化

铅中毒大鼠几种血清酶活性逆向变化的初步探讨

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铅；血清酶；逆向变化,,铅；血清酶；逆向变化,0引言,1材料和方法,2结果,3讨论,【参考文献】

     Primary study on reverse changes of enzyme activities in serum of leadpoisoned rat

    LI ShengLian, ZHOU YingQiong, SHI QingFeng, LUO Yun,YANG Jun, OU ChaoYan, HUANG YuMei, CHEN Xiang, YING Xiang

    Department of Preventive Medicine, Department of Pathology, Department of Clinical Laboratory,Affiliated Hospital, Grade 2002, Department of Clinical Medicine, Guilin Medical College, Guilin 541004, China

    【Abstract】AIM: To understand the mechanism underlying the reverse changes of enzyme activity in serum of rat poisoned by lead. METHODS: Female Wistar rats were randomly divided into 4 groups: control group treated with distilled water; lead groups treated with 10, 30 and 60 mg/kg PbAc2 , respectively,ip, once every 2 d, for 7 times. Subsequently, all animals were sacrificed for measuring the activity of ALT, AST, ALP, LDH and γGT in serum . The serum of rats treated with different concentration of PbAc2 (0, 30 and 300 μmol/L) was incubated in 37℃. Three hours later, the activities of ALT, AST, LDH, ALP and γGT in the serum were assayed. RESULTS: In vivo, compared with the control group, the activities of AST,γGT in serum were significantly higher ......

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