胆管癌浸润转移途径及其机制
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郑秀海, 王曙光
胆管癌;浸润;转移,郑秀海,王曙光,通讯作者:,Advanceinthestudyofinvasionandmetastasisofcholangiocarcinoma,Xiu-HaiZheng,Shu-GuangWang,Correspondence
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郑秀海, 中国人民解放军第401医院肝胆外科 山东省青岛市 266071
王曙光, 第三军医大学全军肝胆外科研究所 重庆市 400038
通讯作者: 王曙光, 400038, 重庆市, 第三军医大学全军肝胆外科研究所. sgwang90@yahoo.com
电话: 023-68754181
收稿日期: 2006-09-20 接受日期: 2006-09-25
Advance in the study of invasion and metastasis of cholangiocarcinoma
Xiu-Hai Zheng, Shu-Guang Wang
Xiu-Hai Zheng,Department of Hepatobiliary Surgery, the 401st Hospital of Chinese PLA, Qingdao 266071, Shandong Province, China
Shu-Guang Wang,Hepatobiliary Surgery Institute of Chinese PLA, the Third Military Medical University, Chongqing 400038, China
Correspondence to:Shu-Guang Wang, Hepatobiliary Surgery Institute of Chinese PLA, the Third Military Medical University, Chongqing 400038, China. sgwang90@yahoo.com
Received:2006-09-20 Accepted:2006-09-25
Abstract
Invasion and metastasis of cholangiocarcinoma have specific characteristics. Lymph node metastasis is one of the metastatic modes of cholangiocarcinoma, and local metastasis occurs more frequently than distal one. Due to the specific anatomic structure of bile duct and its close relation with peripheral nerves and various neuropeptides, perineural invasiveness and metastasis of cholangiocarcinoma are attracting more and more attention in recent years. Besides invasive metastasis, inoculation metastasis, lymphatic metastasis and vascular metastasis, perineural invasiveness and metastasis are important pathological features of cholangiocarcinoma. Study on the mechanism of interaction between nerve fiber and cholangiocarcinoma cells and the regulatory factors during invasion and metastasis of cholangiocarcinoma is one of the hot spots in recent years.
Key Words: Cholangiocarcinoma; Invasion; Metastasis
Zheng XH, Wang SG. Advance in the study of invasion and metastasis of cholangiocarcinoma. Shijie Huaren Xiaohua Zazhi 2007;15(3):276-281
摘要
胆管癌的浸润和转移具有其自身的特点, 经淋巴转移是胆管癌的主要转移方式之一, 以局部淋巴结转移为主, 较少发生远处转移 ......
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