金属硫蛋白在膀胱移行细胞癌中的表达及意义
膀胱癌;金属硫蛋白;免疫组织化学,,膀胱癌;金属硫蛋白;免疫组织化学,关键词:膀胱癌;金属硫蛋白;免疫组织化学,1材料与方法,2结果,3讨论,参考文献:
Expression of metallothionein in bladder transitional cell cacinoma and its clinical significanceHuo Shaojun1, Zhang Ruigang1, Dong Haiyan1, Tian Yunxiao2, Zhang Jianhua1, Gao Shequan1, Zhang Zhenjiang1
(1. Department of Urology; 2. Department of Pathology, the Center Hospital of Handan City, Handan 056001, China)
ABSTRACT: Objective To study the clinical significance of metallothionein in bladder transitional cell cacinoma (BTCC). Methods 72 specimens of BTCC were assessed by immunohistochemical method (SP method). Results Among the 72 cases, the positive rate of metallothionein in Grade Ⅰ, Grade Ⅱ and Grade Ⅲ of BTCC was 34.8%, 55.6% and 92.8%, and was 64% in initial BTCC and 87.3% in recurred BTCC. Conclusion Metallothionein may be a valuable marker of drug resistance, invasive behavior and recurrence in BTCC.
KEY WORDS: bladder transitional cell carcinoma; metallothionein; immunohistochemically
摘要:目的 探讨金属硫蛋白表达在膀胱移行细胞癌治疗及预后方面的临床价值 ......
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