消炎宁痔疮栓药效学研究
消炎宁痔疮栓;,抗炎;,止痛,,消炎宁痔疮栓;,抗炎;,止痛,1材料,2方法,3结果,4讨论
摘要:目的观察消炎宁痔疮栓的药效学作用。方法以小鼠耳肿胀和大鼠足跖肿胀法实验,观察其抗炎作用;应用热板法考察其镇痛作用;用小鼠断尾法观察出血时间。结果消炎宁痔疮栓有明显的抑制小鼠耳肿胀和大鼠足跖肿胀作用(P<0.01);热板法验证消炎宁痔疮栓能明显提高痛阈;小鼠断尾显示其能缩短小鼠尾出血时间。结论消炎宁痔疮栓具有明显的抗炎、镇痛及止血作用。关键词:消炎宁痔疮栓; 抗炎; 止痛
Experimental Study on Pharmacodynamics of XiaoyanningZhichuang Suppository
CAO Yuemei, XIA Anzhou
(Jiangsu Xuzhou MedicalPharmacy Job College,Xuzhou 221000,China;Xuzhou Medical College,Xuzhou 221002,China)
Abstract:ObjectiveTo observe the effectes of antiinflammation,analgesia and hemostasia with XiaoyanningZhichuang Suppository.MethodsThe effects of anti inflammation of XiaoyanningZhichuang Suppository were respectively tested by ear edema of mice,ankle swell of rats.Analgesic experiment was carried out by the method of heat plank.Bleeding time was tested by the cutting tail in mice.ResultsXiaoyanningZhichuang Suppository significantly inhibited the mice ear edema and ankle swell.XiaoyanningZhichuang Suppository remarkably increasesd mice pain threshold and shortened blooding time.ConclusionXiaoyanningZhichuang suppository has obvious effects of antiinflammation,analgesia and hemostasia. ......
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