依达拉奉；_脑梗死；

依达拉奉结合早期康复治疗急性脑梗死60例疗效观察

http://www.100md.com 《实用老年医学》 2000年第1期

依达拉奉；,脑梗死；,老年人,【主题词】依达拉奉；脑梗死；老年人,1对象和方法,2结果,3讨论,参考文献

     【摘要】目的评价依达拉奉注射液治疗急性脑梗死(ACI)的疗效。方法采用随机对照试验，选择发病 48 h内的急性脑梗死患者120例，随机分为依达拉奉组(60例)及对照组(60例)。治疗前及治疗后1月对患者进行神经功能缺损(national institute of health stroke scale，NIHSS)评分、FuglMeyer评分或Barthel指数比较作为主要疗效判断标准。结果治疗后 30 d依达拉奉组NIHSS评分(371±243)较对照组(786±365)降低明显，差异具有统计学意义(P<005)。治疗 30 d后，2组患者的FuglMeyer评分及Barthel指数均明显提高，但依达拉奉组提高幅度明显大于对照组。表明依达拉奉组患者的神经功能缺损恢复程度优于对照组。结论依达拉奉是一种治疗急性缺血性脑卒中有效的神经保护剂。

     【主题词】依达拉奉；脑梗死；老年人

    Effects of edaravone and early rehabilitation on acute cerebral infarction

    LI Guohui，CHEN Hui.

    Department of Neurology，Zhongshan Chinese Medical Hospital，Zhongshan 528400 China

    【Abstract】 Objective To investigate the effects of edaravone on acute cerebral infarction(ACI). Methods A randomized,controlled study was performed.One hundred and sixty patients,who had an onset of ACI within 48 hours,were allocated to edaravone group(n=60)or the control group(n=60)randomly.Before treatment and 30 days after treatment,the neurological deficits(NIHSS),FuglMeyer and Barthel index were evaluated. Resukts There were significant differences between edaravone group(371±243)and the control group(786±365).Thirty days after treatment the improvement of FuglMeyer and Barthel index was significant.The improvement of Edaravone group was more significant than that of the control group. Conckusions Edaravone is a new effective neuroprotective agent in treating ACI. ......

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