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编号:11400662
沙枣治疗婴幼儿急性腹泻病的临床研究
http://www.100md.com 《儿科药学杂志》 2000年第1期
婴幼儿;腹泻;沙枣,,],婴幼儿;腹泻;沙枣,[关键词]婴幼儿;腹泻;沙枣,1对象与方法,2结果,3讨论,参考文献:
     [摘要] 目的:观察比较沙枣与思密达辅助治疗婴幼儿腹泻的疗效。方法:300例急性非重症腹泻病患儿随机分为两组:A组150例用沙枣干粉剂,B组150例用思密达治疗。结果:治疗72 h,A、B两组大便总次数分别减低64.1%和63.3%;每日平均次数较治疗前明显减少(u=9.5,P<0.001),A组水样便由治疗前的72.5%减少至27.5%,脱水患者由75.2%减少为24.8%,与B组结果相近(t=0.74,P=0.4),与治疗前比较差异有统计学意义(u=10.2,P<0.001);每次平均大便量分别减少65.4%和60.0%,差异有统计学意义(t=2.63,P<0.05)。A组和B组每日ORS量分别与治疗初期相比差异有统计学意义(u=10.5,P<0.001),两组间比较差异有统计学意义(t=4.5,P<0.001)。结论:沙枣能减轻腹泻的程度,缩短病程,在减少大便量和ORS的摄入量方面优于思密达。

    [关键词] 婴幼儿;腹泻;沙枣

    A clinical study on the treatment of Elaeagnus angustifolia in infants with acute watery diarrhea

    DUOLIKUN Muzhapaer1, TUERXUNNAYI Yushan1, GULINAER Wulazibieke2

    (1. The First Affiliated Hospital, Xinjiang Medical University, Xinjiang Urumuqi 830054, China; 2. Kelamayi People's Hospital of Xinjiang, Xinjiang Kelamayi 834000, China)

    [Abstract] Objective:In order to explore a cheaper and effective therapy for the acute infantile watery diarrhea in the underdeveloped rural areas, we compared the therapeutic effect of the Elaeagnus angustifolia (EA) with Smecta on acute infantile watery diarrhea. Methods: The 300 pediatric patients with acute nonsevere watery diarrhea were randomly divided into two groups, patients in group A (150 cases) were treated with EA powder plus ORS, while patients in group B (150 cases) with Smecta plus ORS. Results: After 72 hs' treatment the total stool frequency reduced by 64.1% and 63.3% in two groups respectively, with the average frequency of stool per day reduced significantly compared with pretreatment which showed a significant statistical difference (u=9.5, P<0.001). The percentage of the watery diarrhea was decreased from 72.5% to 27.5% in group A. Besides, the proportion of the cases with mild and moderate dehydration was decreased from 75.2% to 24.8%. The similar results were in group B (χ2=0.7, P=0.4). There wasn't any statistically significant difference between these two groups. Average volume of diarrhea per time reduced by 65.4% and 60.0% (t=2.63, P<0.01) respectively. The dosage of ORS intake for the patients showing a significantly statistical difference (u=10.5, P<0.001) than that of the earlier stage of disease, there was significantly statistical difference in two groups (t=4.5, P<0.001). Conclusions: EA had the same clinical therapeutic effectiveness with Smecta in treating acute infantile watery diarrhea; EA could reduce both severity and durations of diarrhea disease, and superior to Smecta in decreasing volumes of watery diarrhea and ORS intake. Not only EA can be used for food and medicine but also cheaper than Smecta. ......

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